招生方向：微生物学（学硕），生物化学与分子生物学（学硕），生物与医药（专硕）
联系方式：srli@fjnu.edu.cn QQ/微信：40946045
一、学习与工作经历
2019.07至今 福建师范大学，生命科学学院，讲师，副教授
2014.09 – 2019.03美国University of Nebraska-Lincoln，化学和生化系，博士后
2013.08 – 2014.08山东大学，药学院，博士后
2009.09 – 2013.07厦门大学，生命科学学院，博士
2006.09 – 2009.07福建农林大学，生命科学学院，硕士
2002.09 – 2006.07安徽科技学院，生命科学学院，本科
二、研究方向
1、微生物天然产物及其生物合成：利用基因组挖掘技术，筛选分离和鉴定来源于溶杆菌的新颖天然产物，为新药研发提供先导化合物。
2、抗生素生产菌株遗传改造：通过分子育种手段改造抗生素生产菌株，提高抗生素产量，选育工业生产优良菌种。
三、科研项目
1、福建省科技厅引导性项目，2021N0011，产酶溶杆菌SR01抗植物病原菌活性成分及其生防机制的研究，15万元，2021/08 – 2024/08，在研，主持
2、国家自然科学基金面上项目，81573311，新资源溶杆菌中活性天然产物的发现与生物合成，56万元，2015/01 – 2019/12，结题，参与
四、主要研究论文
(1) Wan Tao#, Li Shanren#, Beltran Guiza Daisy, Schacht Andrew, Becker C. Donald, Zhang Limei. Structural basis of non-canonical transcriptional regulation by the σA-bound iron-sulfur protein WhiB1 in M. tuberculosis. Nucleic Acids Research, 2020,48(2):501-516.
(2) Li Shanren, Wu Xiuli, Zhang Limei, Shen Yuemao, Du Liangcheng. Activation of a cryptic gene cluster in Lysobacter enzymogenes reveals a module/domain portable mechanism of nonribosomal peptide synthetases in the biosynthesis of pyrrolopyrazines. Organic Letters, 2017, 19 (19):5010–5013.
(3) Zhang Juanli#, Li Shanren#, Wu Xingkang, Guo Zhixing, Lu Chunhua, Shen Yuemao. Nam7 hydroxylase is responsible for the formation of the naphthalenic ring in the biosynthesis of neoansamycins. Organic Letters, 2017, 19 (9):2442–2445.
(4) Li Shanren, Li Yaoyao, Lu Chunhua, Zhang Juanli, Zhu Jing, Wang Haoxing, Shen Yuemao. Activating a cryptic ansamycin biosynthetic gene cluster to produce three new naphthalenic octaketide ansamycins with n-pentyl and n-butyl side chains. Organic letters, 2015, 17(15):3706-3709.
(5) Li Shanren, Lu Chunhua, Chang Xiaoyan, Shen yuemao. Constitutive overexpression of asm18 increases the production and diversity of maytansinoids in Actinosynnema pretiosum. Applied microbiology and biotechnology, 2016, 100(6): 2641-2649.
(6) Li Shanren, Lu Chunhua, Ou Jinhuan, Deng Jingjing, Shen Yuemao. Overexpression of hgc1 increases the production and diversity of hygrocins in Streptomyces sp LZ35. RSC Advances, 2015, 5(102):83843-83846.
(7) Li Shanren, Wang Haoxin, Li Yaoyao, Deng Jingjing,Lu Chunhua, Shen Yan, Shen Yuemao. Biosynthesis of hygrocins, antitumor naphthoquinone ansamycins produced by Streptomyces sp. LZ35. Chembiochem, 2014, 15(1):94-102.
(8) Li Shanren, Zhao Guishi, Sun Mingwei, He Haigang, Wang Haoxin, Li Yaoyao, Lu Chunhua, Shen Yuemao. Identification and characterization of the biosynthetic gene cluster of divergolides from Streptomyces sp. W112. Gene, 2014, 544(1):93-99.