博士，副研究员，硕士生导师，福建省高层次人才
福建师范大学生命科学学院，南方生物医学研究中心
联系方式：xmzeng@fjnu.edu.cn理工楼13号楼南407办公室
教育经历：
2012.9-2016.6华中科技大学，化学与化工学院，学士
2016.9-2018.6华中科技大学，国家光电实验室，硕士
2018.9-2021.9华中科技大学，生命科学学院，博士，导师：刘笔锋教授
研究方向：
主要从事生物友好纳米材料在肿瘤代谢调控的创新诊疗策略，重点关注其在糖代谢、谷氨酰胺代谢、胆固醇代谢的代谢干扰治疗及其机制探索。先后主持国家自然科学基金青年项目，福建省科学基金面上项目，福建师范大学院级“溪源江”创新项目等，以第一作者和通讯作者在ACS Nano, Advanced Materials, Advanced Functional Materials, Advanced Science等国际期刊杂志发表相关论文。
文章：
1.Sijie Shao#, Liman Qiu#, Hai Cai, Huilan Zhuang, Yan Chen, Lizhi Jiang*, Xuemei Zeng*, Shuangqian Yan*, Rational Design of a Multifunctional Copper-Cobalt Sulfide Nanozyme for Cholesterol Depletion and Thermo-Resistant Tumor Ablation, Advanced Functional Materials, 2026, 28729
2.Sijie Shao, Huilan Zhuang, Tingjie Bai, Xuemei Zeng, Angelo Homaoun All, Shuangqian Yan*, Bacterial Biohybrids With Dual Magnet and Hypoxia Tropism for Ferroptosis Activation in Deep Tumor Regions, Exploration, 2026, 20240287
3.Xuemei Zeng, Shumin Tang, Guosheng Hu, Yonghong Pang, Sihuang Lin, Shijie Shangguan, Shuangqian Yan*, Xinlin Ruan*, Liling Zheng*, Reprogramming Macrophage Function via Cholesterol Modulation and Redox Signaling Using a Multifunctional Nanoplatform for Postoperative Breast Cancer Management, ACS Nano, 2025, 32444-32459
4.Shuangqian Yan#, Panpan Xue#, Ying Sun#, Tingjie Bai, Sijie Shao, Xuemei Zeng*, Cupric Doping Hollow Prussian Blue Nanoplatform for Enhanced Cholesterol Depletion: A Promising Strategy for Breast Cancer Therapy and Metastasis Inhibition, Advanced Science, 2025, 2409967.
5.Panpan Xue, Huilan Zhuang, Sijie Shao, Tingjie Bai, Xuemei Zeng*, Shuangqian Yan*, Engineering Biodegradable Hollow Silica/Iron Composite Nanozymes for Breast Tumor Treatment through Activation of the “Ferroptosis Storm”, ACS Nano, 2024,
6.Tingjie Bai#, Panpan Xue#, Sijie Shao, Shuangqian Yan*, and Xuemei Zeng*, Cholesterol Depletion-Enhanced Ferroptosis and Immunotherapy via Engineered Nanozyme, Advanced Science, 2024, 2405826.
7.Huilan Zhuang#, Lun Wang#, Sijie Shao, Haitong Jing, Panpan Xue, Tingjie Bai, Jinpeng Deng, Xuemei Zeng*, Xian Qin*, Shuangqian Yan*, Photocatalysis-promoted tumor ferroptosis enabled by MOF-derived black TiO2, Chemical Engineering Journal, 2024, 154204.
8.Panpan Xue, Huilan Zhuang, Tingjie Bai, Xuemei Zeng*, Jinpeng Deng, Sijie Shao, Shuangqian Yan*, Iron (II)-based metal-organic framework nanozyme for boosting tumor ferroptosis through inhibiting DNA damage repair and system Xc-, Journal of Nanobiotechnology, 2024, 22:228.
已授权专利：
1.燕双仟，曾雪梅。一种双金属硫化物纳米探针的制备及应用。已授权 专利号：ZL 2021 1 1320777.2
2.刘笔锋，曾雪梅，杜伟。结构稳定的三棱柱纳米银复合探针及其制备方法与应用。 已授权 专利号：ZL 2019 1 0068197.5
3.刘笔锋，曾雪梅。一种多孔性四氧化三锰纳米探针的制备及应用。 已授权 专利号：ZL 2019 1 1067190.8
4.刘笔锋，曾雪梅。一种金属有机框架纳米材料、其制备与应用。 已授权 专利号：ZL 2019 1 1064937.4
招聘信息:
课题组常年招生具有化学/材料/生物医学等背景的硕士研究生，同时热忱欢迎具有化学、材料、医学、生物器件等研究背景的博士后加盟！
课题组网址：https://www.x-mol.com/groups/yan-shuangqian